Forskning och kliniska studier

Förutom att bidra till hjärnforskningen i allmänhet, har HAPPYneurons forskarteam, i samarbete med erkända forskningsinstitutioner, undersökt de kognitiva övningarnas effekt på olika kliniska tillstånd. Dessutom har oberoende forskare använt övningarna i olika studier. Forskningsresultaten tyder på att programmen är effektiva gentemot de kognitiva dysfunktioner som kan uppträda i samband med ett antal olika tillstånd och sjukdomar. Nedan finns en översikt över forskningsprojekten.

Sökning (ämne, författare, institution osv.):
Status:
2015
2016
«Cognitus & Moi»: A Computer-Based Cognitive Remediation Program for Children with Intellectual Disability
Avslutad
Intellectual disability
Children
+
Forskningsinstitution:
France
Centre Hospitalier le Vinatier, Center of Cognitive Neuroscience, CNRS, University Lyon 1
Ansvarig:
Caroline Demily, Caroline Rigard, Élodie Peyroux, Gabrielle Chesnoy-Servanin, Aurore Morel, Nicolas Franck
Storlek:
30 deltagare
-
2014
Increased activation in Broca’s area after cognitive remediation in schizophrenia
Avslutad
Schizophrenia
fMRI
+
Forskningsinstitution:
Switzerland
Lausanne Hospital
Ansvarig:
Pascal Vianin, Sébastien Urben, Pierre Magistretti, Pierre Marquet, Eleonora Fornari, Laure Jaugey
Storlek:
16 deltagare
-
2011
2013
Cognitive Remediation for Treatment Resistant Depression
Avslutad
Depression
+
2008
2011
Specific vs general cognitive remediation for executive functioning in schizophrenia: a multicenter randomized trial
Avslutad
Schizophrenia
+
Forskningsinstitution:
France
Le Vinatier Hospital - Bron, Cognitive Neuroscience Centre - Lyon, Sainte-Anne Hospital - Paris
Ansvarig:
Nicolas Franck
Storlek:
280 deltagare
-
2004
2006
MNESIS Project – Using the internet as a means of social integration and cognitive stimulation in a residential unit for elderlies
Avslutad
Geriatrics
+
2019
2021
Activation therapy for the treatment of inpatients with depression – protocol for a randomised control trial compared to treatment as usual
Pågående
Depression
+
Forskningsinstitution:
New Zealand
University of Otago, Christchurch
Ansvarig:
Ian RE Averill, Ben Beaglehole, Katie M. Douglas, Jennifer Jordan, Marie T. Crowe, Maree Inder,Cameron J. Lacey, Christopher M. Frampton, Christopher R. Bowie and Richard J. Porter
Storlek:
170 deltagare
-
2019
Is social cognitive training efficient in autism? A pilot single-case study using the RC2S+ program
Avslutad
Social Cognition
Autism
+
Forskningsinstitution:
France
Le Vinatier hospital, Université de Lyon, Institut des Sciences Cognitives, Lyon
Ansvarig:
Elodie Peyroux, Nicolas Franck
Storlek:
1 deltagare
-
2019
2021
Improving Mental Functioning in Patients With Schizophrenia with a Drug and a Computerized Cognitive Training
Pågående
Schizophrenia
Drug
+
Forskningsinstitution:
World
Boehringer Ingelheim
Ansvarig:
40 Sites in 6 countries
Storlek:
200 deltagare
Registering av forskningsprojekt:
Se registering
-
2018
2019
An Evaluation of the Effectiveness and Feasibility of a Cognitive Remediation Program in a Residential Substance Use Treatment Facility
Pågående
Addiction
+
Forskningsinstitution:
Australia
Wattlegrove Rehab Program, University of Queensland, Lives lived well
Ansvarig:
Leanne Hides, Julaine Allan, Anna Thompson, Frances Dark
Storlek:
65 deltagare
Publikation:
I förberedelse/vätande
-
2018
2021
Can multitasking performance of older adults in close-to-real-life scenarios be improved?
Pågående
Multitasking
Geriatrics
+
Forskningsinstitution:
Germany
Technical University of Chemnitz
Ansvarig:
Claudia Voelcker-Rehage, Otmar Bock, Konstantin Wechsler
Storlek:
150 deltagare
-
2018
2021
Examine the effects of prolonged cognitive remediation on sustaining cognitive gains and functional recovery in schizophrenia.
Pågående
Schizophrenia
+
Forskningsinstitution:
Singapore
Institute of Mental Health, Singapore Institute of Technology
Ansvarig:
Ho New Fei, Sim Kang Jimmy, Chee Keong Lee, Chen Guoyang, Wang Mingyuan, Suhailah Bte Abd Shukor, Daniel Poremski
Storlek:
45 deltagare
-
2018
2022
Reducing delirium and dementia risk: A cognitive training intervention of older adults undergoing elective coronary artery bypass grafting surgery
Pågående
Surgery
+
Forskningsinstitution:
Australia
Cognitive Ageing and Impairment Neurosciences Laboratory (CAIN) University of South Australia
Ansvarig:
Danielle Greaves, Hannah Keage, Peter Psaltis, Ashleigh Smith, Michael Worthington, Alice Bourke, Daniel Davis, Amit Lampit, Michael Valenzuela
Storlek:
120 deltagare
-
2017
2018
Experiences With a Cognitive Rehabilitation Program for Five Female Breast Cancer Survivors: A Focus Group Study
Avslutad
Cancer
Focus Group
+
2017
2019
Effect of action-based cognitive remediation on cognition and neural activity in bipolar disorder: study protocol for a randomized controlled trial.
Avslutad
Bipolar
+
Forskningsinstitution:
Denmark
Copenhagen Affective Disorder Research Center (CADIC), Psychiatric Centre Copenhagen, Copenhagen University Hospital, Rigshospitalet
Ansvarig:
Ott CV, Vinberg M, Bowie CR, Christensen EM, Knudsen GM, Kessing LV, Miskowiak KW
Storlek:
58 deltagare
Registering av forskningsprojekt:
Se registering
-
2017
2018
The effects of computer based cognitive rehabilitation in patients with symptoms of visuospatial neglect or hemianopsia after stroke.
Avslutad
Stroke
+
Forskningsinstitution:
Denmark
Bispebjerg Hospital, Department of Neurology, Copenhagen
Ansvarig:
Svaerke K, Omkvist K, Havsteen I, Christensen H
Storlek:
14 deltagare
-
2017
2021
Restoration of Cognitive Function With TDCS and Training in Schizophrenia
Pågående
Schizophrenia
tDCS
+
Forskningsinstitution:
USA
Department of Veterans Affairs Office of Research and Development, Minneapolis VA Health Care System, Minneapolis
Ansvarig:
Tasha Marie Nienow
Storlek:
110 deltagare
Registering av forskningsprojekt:
Se registering
-
2017
2018
A Comparison of two Computer-Assisted Cognitive Training Program Outcomes for Breast Cancer Survivors: A Pilot Study
Avslutad
Cancer
+
Forskningsinstitution:
USA
Department of Occupational Therapy and Rehabilitation Sciences, The University of Texas Medical Branch
Ansvarig:
Theresa Smith, Karen Ratcliff
Storlek:
20 deltagare
-
2016
2018
Clinical response to treatment in inpatients with depression correlates with changes in activity levels and psychomotor speed
Avslutad
Depression
+
Forskningsinstitution:
New Zealand
University of Otago, Christchurch
Ansvarig:
Ian RE Averill, Marie Crowe, Chris M Frampton, Ben Beaglehole, Cameron J Lacey, Jennifer Jordan, Lynere D Wilson, Katie M Douglas and Richard J Porter
Storlek:
24 deltagare
-
2016
2018
An examination of the moderating effects of neurophysiology on treatment outcomes from cognitive training in schizophrenia-spectrum disorders.
Avslutad
Schizophrenia
+
Forskningsinstitution:
Canada
Toronto Centre for Addiction and Mental Health, and Department of Psychology, Queen's University, Kingston ON
Ansvarig:
Best MW, Milanovic M, Shamblaw AL, Muere A, Lambe LJ. Hong IK, Haque MK, Bowie CR.
Storlek:
70 deltagare
-
2016
2018
A Randomized Controlled Trial of Executive Functioning Training Compared With Perceptual Training for Schizophrenia Spectrum Disorders: Effects on Neurophysiology, Neurocognition, and Functioning.
Avslutad
Schizophrenia
+
Forskningsinstitution:
Canada
Department of Psychology and Department of Psychiatry, Queen's University, Kingston, ON
Ansvarig:
Best MW, Milanovic M, Iftene F, Bowie CR
Storlek:
70 deltagare
Registering av forskningsprojekt:
Se registering
-
2016
2017
Effects of simultaneous aerobic and cognitive training on executive functions, cardiovascular fitness and functional abilities in older adults with mild cognitive impairment
Avslutad
MCI
Physical Activity
+
Forskningsinstitution:
France
University Paris Sud, Institut Universitaire de Gériatrie de Montréal, University Hospital of Amiens-Picardie, University of Poitiers
Ansvarig:
Laure Combourieu Donnezan, Alexandra Perrot, Sylvie Belleville, Frédéric Bloch, Gilles Kemoun
Storlek:
69 deltagare
-
2016
2017
Web-Based Cognitive Remediation Improves Supported Employment Outcomes in Severe Mental Illness: Randomized Controlled Trial
Avslutad
SMI
Employment
+
Forskningsinstitution:
Australia
University of Sydney, Macquarie University
Ansvarig:
Anthony WF Harris, Tanya Kosic, Jean Xu, Chris Walker, William Gye, Antoinette Redoblado Hodge
Storlek:
86 deltagare
Registering av forskningsprojekt:
Se registering
-
2016
2018
Helping people with a mental illness obtain work: the Health Optimisation Program for Employment
Avslutad
Mental Illness
Employment
+
Forskningsinstitution:
Australia
St Vincent's Hospital, Melbourne
Ansvarig:
David Castle, Andrea Phillipou, Gaye Moore, Caroline Crosse AM, Anne Miles
Storlek:
100 deltagare
-
2016
2018
The role of cognitive rehabilitation in patients with type 1 diabetes
Avslutad
Diabetes
+
2016
2019
Translational Neuroscience Optimization of GlyT1 Inhibitor
Pågående
Drug
Schizophrenia
+
Forskningsinstitution:
USA
Yale University
Ansvarig:
John H. Krystal
Storlek:
80 deltagare
Registering av forskningsprojekt:
Se registering
Publikation:
I förberedelse/vätande
-
2016
2019
Exploring cognitive training as a non-pharmaceutical therapeutic intervention for people with Huntington’s disease
Avslutad
Huntington’s disease
+
Forskningsinstitution:
UK
Cardiff University in the Cardiff Huntington’s Disease Research Centre
Ansvarig:
Emma Yhnell, Hannah Furby, Rachel S. Lowe, Lucy C. Brookes-Howell, Cheney J. G. Drew, Rebecca Playle, Gareth Watson, Claudia Metzler-Baddeley, Anne E. Rosser & Monica E. Busse
Storlek:
30 deltagare
Registering av forskningsprojekt:
Se registering
-
2016
2017
Evaluation of cognitive tele-rehabilitation program for children with Attention Deficit Hyperactivity Disorder
Avslutad
ADHD
Children
+
Forskningsinstitution:
Spain
Bio functional Studies Institute – Universidad Complutense (Madrid)
Ansvarig:
Elimelech Duarte, Jesus Alvarado, Alejandra Koeneke
Storlek:
100 deltagare
Publikation:
No Publication
-
2015
2022
Prevention of Alzheimer’s Disease With CR Plus tDCS in Mild Cognitive Impairment and Depression
Pågående
Alzheimer's Disease
tDCS
MCI
+
Forskningsinstitution:
Canada
Centre for Addiction and Mental Health, Queen's University, Baycrest Centre for Geriatric Care
Ansvarig:
Benoit Mulsant
Storlek:
500 deltagare
Registering av forskningsprojekt:
Se registering
-
2015
2017
Brief executive function training for individuals with severe mental illness: Effects on EEG synchronization and executive functioning.
Avslutad
SMI
EEG
Executive Functionning
+
Forskningsinstitution:
Canada
Toronto Centre for Addiction and Mental Health, and University of Toronto Department of Psychiatry
Ansvarig:
Best MW, Gale D, Tran T, Haque MK, Bowie CR
Storlek:
25 deltagare
-
2015
2018
A comparison of compensatory and restorative cognitive interventions in early psychosis.
Avslutad
Psychosis
+
Forskningsinstitution:
Canada
Toronto Centre for Addiction and Mental Health, and University of Toronto Department of Psychiatry
Ansvarig:
Kidd SA, Herman Y, Virdee G, Bowie CR, Velligan D, Plagiannakos C, Voineskos A.
Storlek:
56 deltagare
Registering av forskningsprojekt:
Se registering
-
2015
2018
Evaluation of Dallas Metrocare’s Enhanced Program for Early Psychosis (ePEP)
Avslutad
Psychosis
+
Forskningsinstitution:
USA
UT Southwestern Medical Center
Ansvarig:
Carol North, Ana Stan, Debra Bushong, Draper Bushanan
Storlek:
90 deltagare
Presentation:
Presentation
-
2015
2016
Effects of Cognitive Remediation on Cognitive and Social Functions in Individuals With Schizophrenia
Avslutad
Schizophrenia
+
Forskningsinstitution:
Japan
Fukushima Medical University School of Medicine, National Center of Neurology and Psychiatry
Ansvarig:
A Katsumi, H Hoshino, S Fujimoto, H Yabe, E Ikebuchi, K Nakagome, S-I Niwa
Storlek:
44 deltagare
-
2015
2020
The FOCUS trial: cognitive remediation plus standard treatment versus standard treatment for patients at ultra-high risk for psychosis: study protocol for a randomised controlled trial
Avslutad
Psychosis
+
Forskningsinstitution:
Denmark
Psychiatric Center Copenhagen
Ansvarig:
Louise B Glenthøj, Birgitte Fagerlund, Lasse Randers, Carsten R Hjorthøj, Christina Wenneberg, Kristine Krakauer, Astrid Vosgerau, Christian Gluud, Alice Medalia, David L Roberts, Merete Nordentoft
Storlek:
126 deltagare
Registering av forskningsprojekt:
Se registering
-
2014
2017
Motivation and engagement during cognitive training for schizophrenia spectrum disorders
Avslutad
Schizophrenia
+
Forskningsinstitution:
Canada
Department of Psychology, Queen's University, Kingston, ON
Ansvarig:
Michael W.Best, Melissa Milanovic, Tanya Tran, Pauline Leung, Robyn Jackowich, Stéphanie Gauvin, Talia Leibovitz, Christopher R.Bowie
Storlek:
38 deltagare
-
2014
2019
Manualized group cognitive-behavioral therapy for social anxiety in first episode psychosis: A randomized controlled trial
Pågående
Psychosis
+
Forskningsinstitution:
Canada
Douglas Mental Health University Insitute, Montreal, QC & Department of Psychiatry, McGill University, Montréal QC
Ansvarig:
Martin Lepage, Ashol K. Malla, Philippe-Olivier Harvey, Christopher Bowie
Storlek:
120 deltagare
Registering av forskningsprojekt:
Se registering
-
2014
2019
Effectiveness of metacognitive training (MCT) and cognitive remediation (CR) at treating the persistent symptoms and functional deficits present in those with schizophrenia
Pågående
Schizophrenia
+
Forskningsinstitution:
Canada
University of British Columbia
Ansvarig:
Todd Woodward
Storlek:
75 deltagare
-
2014
2016
Cognitive Training protocols in people with Chronic Pain
Avslutad
Chronic Pain
+
Forskningsinstitution:
Australia
School of Psychological Sciences, Monash University; and Caufiled Pain Management and Research Center, Caulfield Hospital
Ansvarig:
Melita Giummarra, Nellie Georgiou-Karistianis, Stephen Gibson, Katharine Baker
Storlek:
50 deltagare
-
2014
2016
Individualized Metacognitive Training (MCT+) Reduces Delusional Symptoms in Psychosis: A Randomized Clinical Trial
Avslutad
Psychosis
+
2014
2015
Facilitating success for people with mental health issues in a college through cognitive remediation therapy and social and emotional learning
Avslutad
Mental Health
Academic Success
+
Forskningsinstitution:
Canada
CPLS - George Brown College - Saint James Campus - Toronto, Department of Medical Sciences - University of Western Ontario
Ansvarig:
Jaswant Kaur Bajwa, Alex Irwin
Storlek:
21 deltagare
-
2014
2017
Cognitive training to improve language comprehension for seniors?
Avslutad
Geriatrics
+
Forskningsinstitution:
Germany
Jean-Uhrmacher Institut für klinische HNO-Forschung, Klinik und Poliklinik für Neurologie der Uniklinik Köln, Lehrstuhl für Pädagogik und Didaktik hörgeschädigter Menschen
Ansvarig:
Magdalene Ortmann, Harmut Meister, Josef Kessler, Thomas Kaul
Storlek:
50 deltagare
Publikation:
No Publication
-
2013
2015
Effects and efficacy of specialized social cognitive therapy compared to cognitive remediation therapy in people with schizophrenia
Avslutad
Schizophrenia
Social Cognition
+
Forskningsinstitution:
Canada
McGill University Psychiatry Department
Ansvarig:
Philippe-Olivier Harvey, Martin Lepage, Vickie Auclair
Storlek:
40 deltagare
Publikation:
No publication
-
2013
2014
Cognitive remediation for neuropsychological impairment in hoarding disorder: A pilot study
Avslutad
Hoarding Disorder
+
2012
Conditions for Maximizing Effects of 90 Days of Brain Training
Avslutad
General Population
+
Forskningsinstitution:
France
Scientific Brain Training
Ansvarig:
Franck Tarpin-Bernard, Bernard Croisile
Storlek:
350 deltagare
-
2011
2013
Action-based cognitive remediation for individuals with serious mental illnesses: Effects of real-world simulations and goal setting
Avslutad
SMI
+
2011
Increased employability of the unemployed aged 50+ through cognitive training?
Avslutad
Employment
+
Forskningsinstitution:
Germany
Jacobs Center on Lifelong Learning & Research Institutional Development, Jacobs University Bremen
Ansvarig:
B. Godde, C. M. G. Noack, C. Windisch & C. Voelcker-Rehage
Storlek:
87 deltagare
Presentation:
Presentation
-
2010
2011
Cognitive Remediation Early Episode vs. Chronic Outpatients with Schizophrenia
Avslutad
Schizophrenia
+
2007
Alzheimer’s patients maintain cognitive skills and improve self confidence
Avslutad
Alzheimer's Disease
+
Forskningsinstitution:
France
Sophia’s Gardens, Alzheimer’s disease clinic, Castelnau-le-Lez
Ansvarig:
Dr. Foare
Storlek:
47 deltagare
-
2007
Effects of a Brain Wellness Program on Neuropsychological Testing and PET Scans
Avslutad
General Population
fMRI
+
Forskningsinstitution:
USA
Johnny Orr Memory Center, Iowa Health System, Funded by the Center for Disease Control
Ansvarig:
Robert Bender III, David Michael, Derek Campbell, Charles DePena
-
2006
2008
Exploratory Investigation of a Customized cognitive remediation program for individuals living with schizophrenia.
Avslutad
Schizophrenia
+
2006
Memory Stimulation. Which scientific benefits? Which exercises?
Avslutad
Geriatrics
+
Forskningsinstitution:
France
Scientific Brain Training
Ansvarig:
Bernard Croisile et al
Storlek:
39 deltagare
-
2001
2002
Transferability of Cognitive Training to every-day activities (AKA King 64)
Avslutad
Children
+
Forskningsinstitution:
France
EMC laboratory (Université Lyon II – CNRS)
Ansvarig:
Michel Noir, Ph.D
Storlek:
117 deltagare
Publikation:
Thesis
-

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